Are omega-3s helpful for peripheral neuropathy?
I have been diagnosed with pudendal nerve neuropathy. I understand that Omega-3s could be useful for peripheral neuropathies! Is there any truth to this? Thank you.
Dear Giovanni,
In the case of peripheral neuropathies, the most recommended dietary supplement is definitely alpha-lipoic acid (ALA), so my advice is to consult your doctor to start supplementation with this substance.
Alpha-lipoic acid, due to its antioxidant and neuroprotective activity, is the only natural active principle recommended for the treatment of chronic pain in various types of neuropathies. Supplementation with alpha-lipoic acid can be combined with omega-3 fatty acids DHA and EPA, which is useful for several reasons:
- Omega-3s are incorporated into the membranes of all cells, including those of the central and peripheral nervous system. Within the membranes, omega-3s determine important functions of the neurons themselves and regulate nerve signal transduction.
- DHA and EPA are precursors of molecules called "resolvins," which have a significant immunomodulatory and anti-inflammatory effect, both peripherally and in the central nervous system. This effect allows for a progressive reduction in the use of anti-inflammatory drugs employed for pain symptoms.
- The combination of DHA with alpha-lipoic acid increases the absorption and efficacy of alpha-lipoic acid compared to its single intake. The product from our line that I recommend you try is VitaDHA 1000, at a dosage of 2-3 capsules per day to be taken with a meal. It is a dietary supplement based on purified and concentrated fish oil, containing mostly DHA. Each capsule provides 470 mg of DHA and 100 mg of EPA.
If swallowing capsules is difficult, you can opt for VitaDHA liquid, available in single-dose vials of 6 g lemon-flavored fish oil. In this case, the dosage is one vial per day. I remain available for further needs and recommend that you inform your doctor if you decide to start omega-3 supplementation, especially if you are taking concomitant medications.
Best regards,
Rosaria Ramondino Pharmacist and Pharmaceutical Chemist



