What is the difference between fish-derived and plant-derived Omega-3s?
Dear Mr. D’Amico,
I am replying to your question by providing an overview of the different sources of Omega-3.
Animal-Based Omega-3 (Fish-Derived)
The Omega-3 fatty acids found in fish are long-chain:
- Eicosapentaenoic acid (EPA)
- Docosahexaenoic acid (DHA)
Numerous scientific studies highlight the benefits of EPA and DHA Omega-3s:
- anti-inflammatory properties
- anti-thrombotic action
- immunomodulatory activity
- protection of the cardiovascular system
Plant-Based Omega-3
The Omega-3 fatty acids from plant sources are polyunsaturated fats with up to 18 carbon atoms. The main one is alpha-linolenic acid (ALA), which is abundant in walnuts and flaxseeds. However, ALA must be converted by the body into its biologically active forms—EPA and DHA. This conversion is very inefficient (only 1–5% of ALA converts into EPA and just 0.1–0.5% into DHA), and is influenced by several factors:
- age
- stress
- physical fatigue
Because ALA metabolic conversion is problematic for most people, it is extremely beneficial (and often essential) to obtain EPA and DHA directly through the diet.
Algal Omega-3 (Algae-Derived)
EPA and DHA are also found in algae-derived oils. For example, we use these ingredients in our children’s supplement Omegor Kids. I hope this explanation was clear and I remain available for any further information.
Best regards,
Dr. Rosaria Ramondino Pharmacist and Pharmaceutical Chemist



