Nervous System

What is the best supplement for the brain?

Investing in brain nutrition today means protecting cognitive potential and quality of life tomorrow. There's no magic wand, but nutrition provides concrete help. And where what you eat is not enough, products specifically formulated to provide adequate brain support can be a valuable aid. But what is the best brain supplement? Discover the most researched and promising ingredients!

The brain is a complex and dynamic organ, an extraordinary network of billions of neurons that needs constant nourishment to function optimally.

Indeed, from the developmental stage in the womb to old age, our cognitive abilities – such as memory, attention, reasoning, and planning – are strictly dependent on the availability of nutrients that support the structure and functioning of this organ.

Often we get lost in the search for a superfood or a single miraculous nutrient; in reality, science suggests that cognitive performance and brain longevity are the result of a set of eating habits followed throughout life. There is even a dietary regimen (the so-called MIND diet, or Mediterranean-DASH Intervention for Neurodegenerative Delay) specifically studied to delay neurodegeneration and keep the brain younger.

However, meeting the brain's daily needs through diet alone can be complex. Can supplements provide valuable help? The answer seems to be positive, but the most advanced scientific research indicates that the key to cognitive well-being lies not in a single isolated ingredient, but in a strategic and synergistic combination of essential nutrients.

Among the many products available on the market today, what is the best brain supplement?

DHA: the fundamental building block of the nervous system

Among the essential ingredients is docosahexaenoic acid (DHA), one of the fish Omega 3 fatty acids, crucial for supporting memory, attention, and executive functions.

DHA is an irreplaceable structural component of our brain: in adults, it accounts for 15-20% of the fats present in the frontal cortex and 40% of all polyunsaturated fatty acids present in the organ. Its particular chemical structure gives neuron membranes the fluidity and flexibility essential for efficient nervous signal transmission.

For school-aged children, it is a crucial ally for neurocognitive development: 

  • the maturation of the frontal lobes, responsible for executive functions (such as problem-solving and critical thinking), is closely associated with DHA accumulation;
  • adequate DHA levels or its intake from supplements containing it have been associated with improved reading, spelling, and learning abilities, especially in children with initial difficulties;
  • reduced Omega 3 levels have been associated with attention deficit hyperactivity disorder (ADHD);
  • DHA supplementation could help regulate brain activity related to attention;
  • during childhood and adolescence, having sufficient quantities allows neurons to grow and develop new connections, supporting the formation of neural networks.

In adults, however, DHA is often recommended to promote concentration and maintain mental efficiency during daily challenges. Taken alone or in combination with the other Omega 3 present in fish (eicosapentaenoic acid, or EPA) it has been associated with an improvement in mild memory problems typical of aging.

Finally, there is evidence of the ability of Omega 3s to help the brain stay young by promoting the ability to recover or maintain cognitive functions despite advancing age, thanks to their anti-inflammatory and neuroprotective action.

Not just Omega 3: the benefits of GLA and borage oil for membrane integrity

In addition to Omega 3s, among the possible candidates as ingredients for a brain supplement there is also an Omega 6; this is gamma-linolenic acid (GLA), a fat particularly abundant in borage seed oil (Borago officinalis).

Omega 3s (EPA and DHA) and GLA work synergistically against inflammation which, although asymptomatic, can damage nerve cells in the long run.

Furthermore, GLA is important for maintaining the integrity of nerve cell membranes and ensuring adequate blood flow to the nerves, thus promoting proper communication between neurons.

Finally, the interaction between these fats has also proven useful in supporting children with attention deficits and behavioral disorders.

Bacopa monnieri: the memory plant

Another ingredient to consider is Bacopa monnieri. Also known as Brahmi, this plant has been used for millennia in Ayurvedic medicine as a nootropic, that is, as a natural remedy capable of improving mental performance. Its most important active ingredients are bacosides, which act by protecting neurons from oxidative stress and modulating neurotransmitters (in particular acetylcholine).

The benefits of using Bacopa have already emerged in younger individuals. In children between 6 and 8 years old, its intake has been associated with an increase in logical reasoning abilities and exploratory motivation (i.e., the innate need to analyze, know, and understand the surrounding environment).

Furthermore, studies on the patented BacoMind® extract have found improvements in working memory (which allows information to be retained while performing a task) and in visual and auditory memory in children and adolescents aged between 4 and 18 years.

Tests on university students have shown an improvement in cognitive functions and a reduction in distraction during complex tasks. In addition, Bacopa is associated with a reduction in mood swings and stress caused by multitasking.

Finally, bacosides seem to provide a shield against DNA damage to neurons and could help prevent the formation of beta-amyloid protein deposits, associated with neurodegenerative diseases such as Alzheimer's.

Which vitamins and minerals?

Finally, it is important to remember that vitamins and minerals are essential cofactors to allow all brain biochemical processes to take place correctly.

Zinc and vitamin C offer antioxidant protection, defending neurons from free radicals and the brain from oxidative stress. Furthermore, zinc is fundamental for supporting cognitive abilities.

B vitamins, on the other hand, represent energy for the mind. They are often called "energy vitamins," and this also applies to the brain; in addition:

  • they directly support the central nervous system and optimize mental performance;
  • they help reduce fatigue and tiredness, proving valuable for both students under pressure and adults with intense lifestyles;
  • proper intake of B vitamins promotes general psychological well-being, helping to maintain emotional balance.

A synergy for every age

In summary, nourishing the brain does not mean relying on a single nutrient or active ingredient, but ensuring a synergy of substances that work together: DHA for structure, Bacopa for memory, GLA for membrane protection, and vitamins with zinc for metabolic and antioxidant support.

All these precious ingredients – Bacopa monnieri extract (BacoMind®), DHA and EPA of marine origin, borage oil rich in GLA, zinc, vitamin C, and B vitamins – are included in the formulation of Omegor® Mind, a supplement specifically designed to support cognitive functions and nervous system well-being at every stage of life. Discover all its features here!

References:

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Carlson SE, Colombo J. DHA and Cognitive Development. J Nutr. 2021 Nov 2;151(11):3265-3266. doi: 10.1093/jn/nxab299

European Commission. Food and Feed Information Portal Database. Last viewed: 19/02/2026

D'Helft J, Caccialanza R, Derbyshire E, Maes M. Relevance of ω-6 GLA Added to ω-3 PUFAs Supplements for ADHD: A Narrative Review. Nutrients. 2022 Aug 10;14(16):3273. doi: 10.3390/nu14163273

Fatima U, Roy S, Ahmad S, Ali S, Elkady WM, Khan I, Alsaffar RM, Adnan M, Islam A, Hassan MI. Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation. Front Nutr. 2022 Aug 18;9:972379. doi: 10.3389/fnut.2022.972379

Kean JD, Downey LA, Stough C. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med. 2016 Dec;29:56-62. doi: 10.1016/j.ctim.2016.09.002

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McNamara RK, Able J, Jandacek R, Rider T, Tso P, Eliassen JC, Alfieri D, Weber W, Jarvis K, DelBello MP, Strakowski SM, Adler CM. Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study. Am J Clin Nutr. 2010 Apr;91(4):1060-7. doi: 10.3945/ajcn.2009.28549

Mitra-Ganguli T, Kalita S, Bhushan S, Stough C, Kean J, Wang N, Sethi V, Khadilkar A. A Randomized, Double-Blind Study Assessing Changes in Cognitive Function in Indian School Children Receiving a Combination of Bacopa monnieri and Micronutrient Supplementation vs. Placebo. Front Pharmacol. 2017 Nov 17;8:678. doi: 10.3389/fphar.2017.00678

Pei-Chen Chang J. Personalised medicine in child and Adolescent Psychiatry: Focus on omega-3 polyunsaturated fatty acids and ADHD. Brain Behav Immun Health. 2021 Jul 29;16:100310. doi: 10.1016/j.bbih.2021.100310

Sittiprapaporn P, Bumrungpert A, Suyajai P, Stough C. Effectiveness of Fish Oil-DHA Supplementation for Cognitive Function in Thai Children: A Randomized, Doubled-Blind, Two-Dose, Placebo-Controlled Clinical Trial. Foods. 2022 Aug 26;11(17):2595. doi: 10.3390/foods11172595

Tian A, Xu L, Szeto IM, Wang X, Li D. Effects of Different Proportions of DHA and ARA on Cognitive Development in Infants: A Meta-Analysis. Nutrients. 2025 Mar 20;17(6):1091. doi: 10.3390/nu17061091

Usha, P.D. & Wasim, P. & Joshua, J.A. & Geetharani, P. & Balasubramianan, Murali & Mayachari, Anand & Venkateshwarlu, K. & Saxena, V.S. & Mundkinajeddu, Deepak & Agarwal, Amit. (2008). BacoMind®: A Cognitive Enhancer in Children Requiring Individual Education Programme. Journal of Pharmacology and Toxicology. 3. 302-310. doi: 10.3923/jpt.2008.302.310

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OMEGOR Mind - 30 capsules Learn more

OMEGOR Mind - 30 capsules

€18,70

“Why can’t I memorize some things?”. From this question, common to children with learning difficulties and adults over 55, OMEGOR® Mind was born. At the heart of the formula, a patented extract of Bacopa monnieri - Bacomind® - with the addition of Omega-3 EPA and DHA, Omega-6 GLA, zinc and B vitamins. This is how we have transformed the age-old wisdom of Ayurvedic medicine into a formula with scientifically proven results. 

 

Serving Size: 2
Number of servings: 15
Lot and expiry: 230608 - October 2026